Onecut3

Spatial tier: RESTRICTED · Class: OTHER · Top region: B (Barrington's nucleus) · Positive regions: 23/554

46.5Discovery Score

40.0Targetability Score

CEvidence grade C

What this means: Onecut3: fine CCF profile is restricted toward B (top regions: B, RCH, OV, MEPO, AVPV; 23 positive regions); direct spatial validation is still required.

Priority review: This gene was requested explicitly and is shown even if the spatial gate rejected it. Treat this as a hypothesis/evidence record, not as a confirmed region-specific call.

Direct spatial evidence

Allen ISH experiment 81655213, image 81627767 -- target region: B (Barrington's nucleus)

Allen ISH experiment 81655213, image 81627769 -- target region: B (Barrington's nucleus)

Regional expression figure

Predicted WMB × fine-CCF profile; not direct full-transcriptome spatial measurement.

CCF fine-region location

Region-centroid map colored by predicted expression; not a direct cellular expression image.

Spatial profile

1.59

RCH

1.52

1.22

MEPO

1.13

AVPV

0.726

0.72

AHN

0.66

VLPO

0.627

SCH

0.614

PeF

0.594

SBPV

0.566

PVa

0.54

0.528

SLC

0.502

SLD

0.481

PRP

0.443

0.44

DMX

0.435

SUT

0.406

SOCl

0.395

Evidence and specificity

Evidence status: PREDICTED_FINE
Direct sources: None; predicted localization only
Exclusive threshold: 12 positive regions out of 554
Spatial specificity: 0.325
Top-region fraction: 0.064
Filter status: PASS

Interpretation limits

Cell-type-to-region projection is imputed expression, not direct spatial measurement.
Adult reference atlases do not establish stability across age, sex, strain, state, or disease.
Transcript abundance does not guarantee protein abundance or genetic-tool performance.